# GLP-1 Weight Loss Calculator > A free, clinical-trial-backed calculator that projects personalized week-by-week weight loss for GLP-1 medications including Ozempic, Wegovy, Mounjaro, Zepbound, semaglutide, and tirzepatide. ## About This Tool The GLP-1 Weight Loss Calculator at glp1weightlosscalculator.com helps users estimate their weight loss journey on GLP-1 receptor agonist medications. It uses data from landmark clinical trials (STEP-1 for semaglutide, SURMOUNT-1 for tirzepatide) to generate personalized projections based on current weight, height, age, gender, and target weight. ## Supported Medications - **Ozempic** (semaglutide) — GLP-1 agonist, ~12% average weight loss, max dose 2.0 mg/week - **Wegovy** (semaglutide) — GLP-1 agonist, ~15% average weight loss, max dose 2.4 mg/week - **Mounjaro** (tirzepatide) — Dual GIP/GLP-1 agonist, ~22% average weight loss, max dose 15 mg/week - **Zepbound** (tirzepatide) — Dual GIP/GLP-1 agonist, ~20% average weight loss, max dose 15 mg/week - **Generic Semaglutide** — GLP-1 agonist, ~15% average weight loss, max dose 2.4 mg/week - **Generic Tirzepatide** — Dual GIP/GLP-1 agonist, ~22% average weight loss, max dose 15 mg/week - **Retatrutide** (investigational) — Triple GIP/GLP-1/Glucagon agonist, ~24% average weight loss (phase 2), max dose 12 mg/week ## Key Clinical References 1. Wilding JPH et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989-1002. PMID: 33567185 2. Jastreboff AM et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216. PMID: 35658024 3. Wilding JPH et al. Weight regain after withdrawal of semaglutide: STEP 1 extension. Diabetes Obes Metab. 2022;24(8):1553-1564. PMID: 35441470 4. van Sloten TT et al. Projected life-year gains with semaglutide (SELECT trial). Endocr Connect. 2026. PMID: 41800807 5. Jastreboff AM et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. N Engl J Med. 2023;389(6):514-526. PMID: 37366315 ## How It Works 1. User selects a GLP-1 medication 2. User enters current weight, height, age, gender, and target weight 3. Calculator generates a week-by-week weight loss projection chart 4. Results include personalized dosing timeline, calorie/protein recommendations, and estimated weeks to goal ## Frequently Asked Questions - How much weight can you lose on Ozempic? Average 14.9% body weight over 68 weeks (STEP-1 trial) - How much weight can you lose on Mounjaro? Average 22.5% body weight over 72 weeks (SURMOUNT-1 trial) - What is Retatrutide? An investigational triple GIP/GLP-1/Glucagon agonist that achieved 24.2% weight loss in a phase 2 trial — the most effective weight loss medication studied to date - What is the difference between semaglutide and tirzepatide? Semaglutide is a GLP-1 agonist; tirzepatide is a dual GIP/GLP-1 agonist with higher average weight loss - Are GLP-1 medications safe? FDA-approved for weight management; common side effects include nausea that improves over time; SELECT trial showed cardiovascular benefits - How long to see results? Noticeable weight loss within 4 weeks; significant results after 3-6 months at higher doses - What happens if you stop? STEP-1 extension showed ~2/3 of lost weight regained within 1 year of stopping ## Full Content For the complete detailed version of this site's content, see: https://www.glp1weightlosscalculator.com/llms-full.txt ## Contact Website: https://www.glp1weightlosscalculator.com